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Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer’s disease

OBJECTIVE: The double transgenic mouse model (APPswe/PS1dE9) of Alzheimer’s disease (AD) has been widely used in experimental studies. β-Amyloid (Aβ) peptide is excessively produced in AD mouse brain, which affects synaptic function and the development of central nervous system. However, little has...

詳細記述

保存先:
書誌詳細
出版年:Neurosci Bull
主要な著者: Xiong, Huaqi, Callaghan, Debbie, Wodzinska, Jolanta, Xu, Jiejing, Premyslova, Maryna, Liu, Qing-Yan, Connelly, John, Zhang, Wandong
フォーマット: Artigo
言語:Inglês
出版事項: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560305/
https://ncbi.nlm.nih.gov/pubmed/21788993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-011-1015-7
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