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Myt1l induced direct reprogramming of pericytes into cholinergic neurons

OBJECTIVE: The cholinergic deficit is thought to underlie progressed cognitive decline in Alzheimer Disease. The lineage reprogramming of somatic cells into cholinergic neurons may provide strategies toward cell‐based therapy of neurodegenerative diseases. METHODS AND RESULTS: Here, we found that a...

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Bibliographische Detailangaben
Veröffentlicht in:CNS Neurosci Ther
Hauptverfasser: Liang, Xing‐Guang, Tan, Chao, Wang, Cheng‐Kun, Tao, Rong‐Rong, Huang, Yu‐Jie, Ma, Kui‐Fen, Fukunaga, Kohji, Huang, Ming‐Zhu, Han, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490008/
https://ncbi.nlm.nih.gov/pubmed/29453933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12821
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