Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program

Ectopic expression of defined transcription factors can force direct cell fate conversion from one lineage to another in the absence of cell division. Several transcription factor cocktails have enabled successful reprogramming of various somatic cell types into induced neurons (iNs) of distinct neu...

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Udgivet i:Nat Neurosci
Main Authors: Karow, Marisa, Camp, J. Gray, Falk, Sven, Gerber, Tobias, Pataskar, Abhijeet, Gac-Santel, Malgorzata, Kageyama, Jorge, Brazovskaja, Agnieska, Garding, Angela, Fan, Wenqiang, Riedemann, Therese, Casamassa, Antonella, Smiyakin, Andrej, Schichor, Christian, Götz, Magdalena, Tiwari, Vijay K., Treutlein, Barbara, Berninger, Benedikt
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319609/
https://ncbi.nlm.nih.gov/pubmed/29915193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0168-3
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