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Whole‐exome sequencing reveals microsatellite DNA markers for response to dofetilide initiation in patients with persistent atrial fibrillation: A pilot study

BACKGROUND: Dofetilide is a class III antiarrhythmic drug effective for the treatment of atrial fibrillation (AF). Dofetilide initiation (DI) associates with corrected QT interval (QTc) prolongation. Significant QTc prolongation during DI mandates dose adjustment or discontinuation of the drug. Micr...

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Detalhes bibliográficos
Publicado no:Clin Cardiol
Main Authors: Kinney, Nick, Larsen, Timothy R., Kim, David M., Varghese, Robin T., Poelzing, Steven, Garner, Harold R., AlMahameed, Soufian T.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489891/
https://ncbi.nlm.nih.gov/pubmed/29671888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clc.22969
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