Functionalized docetaxel-loaded lipid-based-nanosuspensions to enhance antitumor efficacy in vivo

Purpose: To further enhance the antitumor efficacy through targeted delivery, DTX loaded lipid-based-nanosuspensions (DTX-LNS) were prepared and functionalized by PEGylation or NGR modification to develop DSPE-PEG(2000) modified DTX-LNS (P-DTX-LNS) or DSPE-PEG(2000)-NGR modified DTX-LNS (N-DTX-LNS),...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Pang, Xiuping, Wang, Tianqi, Jiang, Dandan, Mu, Weiwei, Zhang, Bo, Zhang, Na
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489590/
https://ncbi.nlm.nih.gov/pubmed/31114190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S191341
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