Peri-tumor fibroblasts promote tumorigenesis and metastasis of hepatocellular carcinoma via Interleukin6/STAT3 signaling pathway

Purpose: Because many hepatocellular carcinoma (HCC) cases develop from fibrotic or cirrhotic livers, fibroblasts are abundant in the microenvironment of HCC. Although the contribution of cancer-associated fibroblasts (CAFs) to the progression of HCC is well established, the role of fibroblasts has...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Zhao, Zhenxiong, Xiong, Si, Wang, Ronghua, Li, Yawen, Wang, Xiju, Wang, Yun, Bai, Shuya, Chen, Wei, Zhao, Yuchong, Cheng, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489558/
https://ncbi.nlm.nih.gov/pubmed/31118769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S192263
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