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miR-140-5p could suppress tumor proliferation and progression by targeting TGFBRI/SMAD2/3 and IGF-1R/AKT signaling pathways in Wilms’ tumor

BACKGROUND: Wilms’ tumor is also called nephroblastoma and is the most common pediatric renal cancer. Several genetic and epigenetic factors have been found to account for the development of Wilms’ tumor. MiRNAs play important roles in this tumorigenic process. In the present study, we aimed to inve...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Liu, Zhuo, He, Feng, OuYang, Shengrong, Li, Yuanyuan, Ma, Feifei, Chang, Huibo, Cao, Dingding, Wu, Jianxin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489324/
https://ncbi.nlm.nih.gov/pubmed/31035970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5609-1
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