All-trans-retinoic acid (ATRA) plus oxaliplatin plus 5-fluorouracil/leucovorin (FOLFOX) versus FOLFOX alone as palliative chemotherapy in patients with advanced hepatocellular carcinoma and extrahepatic metastasis: study protocol for a randomized controlled trial

BACKGROUND: Among patients with hepatocellular carcinoma (HCC), 85% of patients have an advanced disease stage at diagnosis and curative therapies cannot be performed. Prognosis has been quite poor as until recently there was no proven effective chemotherapy. Our group found that all-trans-retinoic...

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Bibliografiske detaljer
Udgivet i:Trials
Main Authors: Shi, Jie, Sun, Juxian, Liu, Chang, Chai, Zongtao, Wang, Nanya, Zhang, Hui, Cheng, Shuqun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Study Protocol
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489221/
https://ncbi.nlm.nih.gov/pubmed/31036040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3349-9
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