A randomized phase II study to compare oxaliplatin plus 5-fluorouracil and leucovorin (FOLFOX4) versus oxaliplatin plus raltitrexed (TOMOX) as first-line chemotherapy for advanced colorectal cancer

INTRODUCTION: The aim of this study was to compare TOMOX versus FOLFOX4 as first-line treatment of advanced colorectal cancer (CRC). MATERIALS AND METHODS: 191 chemotherapy-naïve patients were randomized to receive TOMOX or FOLFOX4. Patients were evaluated every 3 months and chemotherapy was continu...

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Detalhes bibliográficos
Main Authors: Gravalos, Cristina, Salut, Antonieta, García-Girón, Carlos, García-Carbonero, Rocío, León, Ana Isabel, Sevilla, Isabel, Maurel, Joan, Esteban, Beatriz, García-Rico, Eduardo, Murias, Adolfo, Cortés-Funes, Hernán
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Milan 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427491/
https://ncbi.nlm.nih.gov/pubmed/22855138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12094-012-0843-x
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