Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci

Adolescent idiopathic scoliosis (AIS) is the most common musculoskeletal disorder of childhood development. The genetic architecture of AIS is complex, and the great majority of risk factors are undiscovered. To identify new AIS susceptibility loci, we conducted the first genome-wide meta-analysis o...

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Udgivet i:Hum Mol Genet
Main Authors: Khanshour, Anas M, Kou, Ikuyo, Fan, Yanhui, Einarsdottir, Elisabet, Makki, Nadja, Kidane, Yared H, Kere, Juha, Grauers, Anna, Johnson, Todd A, Paria, Nandina, Patel, Chandreshkumar, Singhania, Richa, Kamiya, Nobuhiro, Takeda, Kazuki, Otomo, Nao, Watanabe, Kota, Luk, Keith D K, Cheung, Kenneth M C, Herring, John A, Rios, Jonathan J, Ahituv, Nadav, Gerdhem, Paul, Gurnett, Christina A, Song, You-Qiang, Ikegawa, Shiro, Wise, Carol A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Association Studies Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488972/
https://ncbi.nlm.nih.gov/pubmed/30395268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy306
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