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MGCD0103, a selective histone deacetylase inhibitor, coameliorates oligomeric Aβ(25‐35)‐induced anxiety and cognitive deficits in a mouse model

AIMS: Recently, histone deacetylase (HDAC) inhibitors are considered a possible therapeutic strategy in Alzheimer's disease (AD). However, HDACi treatments exhibit diverse functions with unfavorable effects in AD. Thus, the development of selective HDACi without side effects is urgently needed....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:CNS Neurosci Ther
Päätekijät: Huang, Hei‐Jen, Huang, Hsin‐Yu, Hsieh‐Li, Hsiu Mei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488906/
https://ncbi.nlm.nih.gov/pubmed/29978554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13029
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