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SIRT3 activator honokiol ameliorates surgery/anesthesia‐induced cognitive decline in mice through anti‐oxidative stress and anti‐inflammatory in hippocampus

AIMS: Increasing evidence indicates that neuroinflammatory and oxidative stress play two pivotal roles in cognitive impairment after surgery. Honokiol (HNK), as an activator of Sirtuin3 (SIRT3), has potential multiple biological functions. The aim of these experiments is to evaluate the effects of H...

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Publicado en:CNS Neurosci Ther
Main Authors: Ye, Ji‐Shi, Chen, Lei, Lu, Ya‐Yuan, Lei, Shao‐Qing, Peng, Mian, Xia, Zhong‐Yuan
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488903/
https://ncbi.nlm.nih.gov/pubmed/30296006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13053
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