DPP‐4 inhibitors promote proliferation and migration of rat brain microvascular endothelial cells under hypoxic/high‐glucose conditions, potentially through the SIRT1/HIF‐1/VEGF pathway

BACKGROUND: Vascular disease in diabetes, for example, stroke, presents a significant public health burden. Recently, the dipeptidyl peptidase 4 (DPP‐4) inhibitor linagliptin has been found to counteract stroke among diabetic patients, showing great promise in drug repurposing and indication expansi...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:CNS Neurosci Ther
Auteurs principaux: Mi, Dong‐Hua, Fang, Hong‐Juan, Zheng, Guang‐Hui, Liang, Xian‐Hong, Ding, Ya‐Rong, Liu, Xin, Liu, Li‐Ping
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488877/
https://ncbi.nlm.nih.gov/pubmed/30136405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13042
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires