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FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human
Several tolerance checkpoints exist throughout B cell development to control autoreactive B cells and prevent the generation of pathogenic autoantibodies. FcγRIIb is an Fc receptor that inhibits B cell activation and, if defective, is associated with autoimmune disease, yet its impact on specific B...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6488660/ https://ncbi.nlm.nih.gov/pubmed/31036800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09434-0 |
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