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Coumarin derivatives as acetyl- and butyrylcholinestrase inhibitors: An in vitro, molecular docking, and molecular dynamics simulations study

Alzheimer's disease is an irreversible and progressive brain disease that can cause problems with memory and thinking skills. It is characterized by loss of cognitive ability and severe behavioral abnormalities, and could lead to death. Cholinesterases (ChEs) play a crucial role in the control...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Abu-Aisheh, Marwa N., Al-Aboudi, Amal, Mustafa, Mohammad S., El-Abadelah, Mustafa M., Ali, Saman Yousuf, Ul-Haq, Zaheer, Mubarak, Mohammad S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488543/
https://ncbi.nlm.nih.gov/pubmed/31183424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2019.e01552
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