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Genetic, epigenetic and posttranscriptional mechanisms for treatment of major depression: the 5-HT1A receptor gene as a paradigm

Major depression and anxiety are highly prevalent and involve chronic dysregulation of serotonin, but they remain poorly understood. Here, we review novel transcriptional (genetic, epigenetic) and posttranscriptional (microRNA, alternative splicing) mechanisms implicated in mental illness, focusing...

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Bibliographische Detailangaben
Veröffentlicht in:J Psychiatry Neurosci
Hauptverfasser: Albert, Paul R., Le François, Brice, Vahid-Ansari, Faranak
Format: Artigo
Sprache:Inglês
Veröffentlicht: Joule Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488484/
https://ncbi.nlm.nih.gov/pubmed/30807072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.180209
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