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Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency
During early mammalian development, the chromatin landscape undergoes profound transitions. The Zdbf2 gene—involved in growth control—provides a valuable model to study this window: upon exit from naïve pluripotency and prior to tissue differentiation, it undergoes a switch from a distal to a proxim...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6488298/ https://ncbi.nlm.nih.gov/pubmed/30990414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44057 |
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