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The role of tonic glycinergic conductance in cerebellar granule cell signalling and the effect of gain‐of‐function mutation

KEY POINTS: A T258F mutation of the glycine receptor increases the receptor affinity to endogenous agonists, modifies single‐channel conductance and shapes response decay kinetics. Glycine receptors of cerebellar granule cells play their functional role not continuously, but when the granule cell la...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Physiol
Päätekijät: McLaughlin, Catherine, Clements, John, Oprişoreanu, Ana‐Maria, Sylantyev, Sergiy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487928/
https://ncbi.nlm.nih.gov/pubmed/30875431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277626
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