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The role of tonic glycinergic conductance in cerebellar granule cell signalling and the effect of gain‐of‐function mutation
KEY POINTS: A T258F mutation of the glycine receptor increases the receptor affinity to endogenous agonists, modifies single‐channel conductance and shapes response decay kinetics. Glycine receptors of cerebellar granule cells play their functional role not continuously, but when the granule cell la...
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| Publicado no: | J Physiol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487928/ https://ncbi.nlm.nih.gov/pubmed/30875431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277626 |
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