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The role of lysosomes and autophagosomes in frontotemporal lobar degeneration
INTRODUCTION: Cell biological and genetic evidence implicate failures in degrading aggregating proteins, such as tau and TDP‐43, through the autophagy or lysosomal pathways in the pathogenesis of frontotemporal lobar degeneration (FTLD). METHODS: We investigated changes in the degradative pathways i...
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| Publicado no: | Neuropathol Appl Neurobiol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487817/ https://ncbi.nlm.nih.gov/pubmed/29790198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12500 |
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