The apolipoprotein E ε4 allele selectively increases the risk of frontotemporal lobar degeneration in males

OBJECTIVE: To determine whether polymorphic variations in the apolipoprotein E gene (APOE) are associated with increased risk of frontotemporal lobar degeneration (FTLD) when mutation in tau gene is absent. METHODS: The APOE gene was genotyped by polymerase chain reaction from DNA routinely extracte...

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Detalhes bibliográficos
Main Authors: Srinivasan, R, Davidson, Y, Gibbons, L, Payton, A, Richardson, A M T, Varma, A, Julien, C, Stopford, C, Thompson, J, Horan, M A, Pendleton, N, Pickering‐Brown, S M, Neary, D, Snowden, J S, Mann, D M A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
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Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077587/
https://ncbi.nlm.nih.gov/pubmed/16421115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2005.063966
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