Downregulation of CHIP promotes ovarian cancer metastasis by inducing Snail‐mediated epithelial–mesenchymal transition

The epithelial–mesenchymal transition (EMT) plays a pivotal role in the conversion of early‐stage tumors into invasive malignancies. The transcription factor Snail, an extremely unstable protein whose subcellular levels are regulated by many E3 ubiquitin ligases, promotes EMT as well as associated p...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Park, Sun‐Mi, Park, Seung‐Ho, Ryu, Ki‐Jun, Kim, In‐Kyu, Han, Hyeontak, Kim, Hyo‐Jin, Kim, Seon‐Hee, Hong, Keun‐Seok, Kim, Hyemin, Kim, Minju, Cho, Bok Im, Heo, Jeong Doo, Kim, Na Hyun, Hwang, Eun Mi, Park, Jae‐Yong, Yook, Jong In, Cho, Hee Jun, Hwangbo, Cheol, Kim, Kwang Dong, Song, Hoseok, Yoo, Jiyun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487736/
https://ncbi.nlm.nih.gov/pubmed/30927556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12485
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