Downregulation of CHIP promotes ovarian cancer metastasis by inducing Snail‐mediated epithelial–mesenchymal transition

The epithelial–mesenchymal transition (EMT) plays a pivotal role in the conversion of early‐stage tumors into invasive malignancies. The transcription factor Snail, an extremely unstable protein whose subcellular levels are regulated by many E3 ubiquitin ligases, promotes EMT as well as associated p...

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Опубликовано в: :Mol Oncol
Главные авторы: Park, Sun‐Mi, Park, Seung‐Ho, Ryu, Ki‐Jun, Kim, In‐Kyu, Han, Hyeontak, Kim, Hyo‐Jin, Kim, Seon‐Hee, Hong, Keun‐Seok, Kim, Hyemin, Kim, Minju, Cho, Bok Im, Heo, Jeong Doo, Kim, Na Hyun, Hwang, Eun Mi, Park, Jae‐Yong, Yook, Jong In, Cho, Hee Jun, Hwangbo, Cheol, Kim, Kwang Dong, Song, Hoseok, Yoo, Jiyun
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487736/
https://ncbi.nlm.nih.gov/pubmed/30927556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12485
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