Low-Dose 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Causes Inflammatory Activation of Astrocytes in Nuclear Factor-κB Reporter Mice Prior to Loss of Dopaminergic Neurons

Neuroinflammation is implicated in the progression of numerous disease states of the CNS, but early inflammatory signaling events in glial cells that may predispose neurons to injury are not easily characterized in vivo. To address this question, we exposed transgenic mice expressing a nuclear facto...

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Vydáno v:J Neurosci Res
Hlavní autoři: Miller, James A., Trout, Briana R., Sullivan, Kelly A., Bialecki, Russell A., Roberts, Ruth A., Tjalkens, Ronald B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487665/
https://ncbi.nlm.nih.gov/pubmed/21259327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22549
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