Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer’s Disease – An Emerging Role for Gut Microbiome

INTRODUCTION: Increasing evidence suggests a role for the gut microbiome in central nervous system disorders and specific role for the gut-brain axis in neurodegeneration. Bile acids (BA), products of cholesterol metabolism and clearance, are produced in the liver and are further metabolized by gut...

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Vydáno v:Alzheimers Dement
Hlavní autoři: MahmoudianDehkordi, Siamak, Arnold, Matthias, Nho, Kwangsik, Ahmad, Shahzad, Jia, Wei, Xie, Guoxiang, Louie, Gregory, Kueider-Paisley, Alexandra, Arthur Moseley, M., Will Thompson, J., Williams, Lisa St John, Tenenbaum, Jessica D., Blach, Colette, Baillie, Rebecca, Han, Xianlin, Bhattacharyya, Sudeepa, Toledo, Jon B., Schafferer, Simon, Klein, Sebastian, Koal, Therese, Risacher, Shannon L., Kling, Mitchel Allan, Motsinger-Reif, Alison, Rotroff, Daniel M., Jack, John, Hankemeier, Thomas, Bennett, David A., De Jager, Philip L., Trojanowski, John Q., Shaw, Leslie M., Weiner, Michael W., Doraiswamy, P. Murali, van Duijn, Cornelia M., Saykin, Andrew J., Kastenmüller, Gabi, Kaddurah-Daouk, Rima
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487485/
https://ncbi.nlm.nih.gov/pubmed/30337151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.07.217
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