CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy

Podocyte injury critically contributes to the pathogenesis of obesity-related glomerulopathy (ORG). Recently, lipid accumulation and inflammatory responses have been found to be involved in podocyte injury. This study is to explore their role and relationship in podocyte injury of ORG. In animal exp...

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Vydáno v:Mediators Inflamm
Hlavní autoři: Zhao, Jing, Rui, Hong-liang, Yang, Min, Sun, Li-jun, Dong, Hong-rui, Cheng, Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487104/
https://ncbi.nlm.nih.gov/pubmed/31097920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3172647
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