CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy

Podocyte injury critically contributes to the pathogenesis of obesity-related glomerulopathy (ORG). Recently, lipid accumulation and inflammatory responses have been found to be involved in podocyte injury. This study is to explore their role and relationship in podocyte injury of ORG. In animal exp...

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Detalles Bibliográficos
Publicado en:Mediators Inflamm
Autores principales: Zhao, Jing, Rui, Hong-liang, Yang, Min, Sun, Li-jun, Dong, Hong-rui, Cheng, Hong
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487104/
https://ncbi.nlm.nih.gov/pubmed/31097920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3172647
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