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CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy

Podocyte injury critically contributes to the pathogenesis of obesity-related glomerulopathy (ORG). Recently, lipid accumulation and inflammatory responses have been found to be involved in podocyte injury. This study is to explore their role and relationship in podocyte injury of ORG. In animal exp...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Zhao, Jing, Rui, Hong-liang, Yang, Min, Sun, Li-jun, Dong, Hong-rui, Cheng, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487104/
https://ncbi.nlm.nih.gov/pubmed/31097920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3172647
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