CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy

Podocyte injury critically contributes to the pathogenesis of obesity-related glomerulopathy (ORG). Recently, lipid accumulation and inflammatory responses have been found to be involved in podocyte injury. This study is to explore their role and relationship in podocyte injury of ORG. In animal exp...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mediators Inflamm
Autori principali: Zhao, Jing, Rui, Hong-liang, Yang, Min, Sun, Li-jun, Dong, Hong-rui, Cheng, Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487104/
https://ncbi.nlm.nih.gov/pubmed/31097920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3172647
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