CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy

Podocyte injury critically contributes to the pathogenesis of obesity-related glomerulopathy (ORG). Recently, lipid accumulation and inflammatory responses have been found to be involved in podocyte injury. This study is to explore their role and relationship in podocyte injury of ORG. In animal exp...

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Bibliographic Details
Published in:Mediators Inflamm
Main Authors: Zhao, Jing, Rui, Hong-liang, Yang, Min, Sun, Li-jun, Dong, Hong-rui, Cheng, Hong
Format: Artigo
Language:Inglês
Published: Hindawi 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487104/
https://ncbi.nlm.nih.gov/pubmed/31097920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3172647
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