Tag-based next generation sequencing: a feasible and reliable assay for EGFR T790M mutation detection in circulating tumor DNA of non small cell lung cancer patients

BACKGROUND: The demonstration of EGFR T790M gene mutation in plasma is crucial to assess the eligibility of Non Small Cell Lung Cancer (NSCLC) patients, who have acquired resistance to first or second generation Tyrosine Kinase Inhibitors (TKIs), to receive a subsequent treatment with osimertinib. S...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Dono, Mariella, De Luca, Giuseppa, Lastraioli, Sonia, Anselmi, Giorgia, Dal Bello, Maria Giovanna, Coco, Simona, Vanni, Irene, Grossi, Francesco, Vigani, Antonella, Genova, Carlo, Ferrarini, Manlio, Ravetti, Jean Louis, Zupo, Simona
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487061/
https://ncbi.nlm.nih.gov/pubmed/31029076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-019-0082-5
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