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Inhibition of Fascin in Cancer and Stromal Cells Blocks Ovarian Cancer Metastasis
OBJECTIVE: Ovarian cancer (OvCa) metastasis requires the coordinated motility of both cancer and stromal cells. Cellular movement is a dynamic process that involves the synchronized assembly of f-actin bundles into cytoskeletal protrusions by fascin. Fascin directly binds factin and is an integral c...
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| Publicado no: | Gynecol Oncol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486884/ https://ncbi.nlm.nih.gov/pubmed/30797592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2019.01.020 |
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