Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum

Ascofuranone (AF) and ascochlorin (AC) are meroterpenoids produced by various filamentous fungi, including Acremonium egyptiacum (synonym: Acremonium sclerotigenum), and exhibit diverse physiological activities. In particular, AF is a promising drug candidate against African trypanosomiasis and a po...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Araki, Yasuko, Awakawa, Takayoshi, Matsuzaki, Motomichi, Cho, Rihe, Matsuda, Yudai, Hoshino, Shotaro, Shinohara, Yasutomo, Yamamoto, Masaichi, Kido, Yasutoshi, Inaoka, Daniel Ken, Nagamune, Kisaburo, Ito, Kotaro, Abe, Ikuro, Kita, Kiyoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486709/
https://ncbi.nlm.nih.gov/pubmed/30952781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819254116
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