Simultaneous determination of intracellular concentrations of tenofovir, emtricitabine, and dolutegravir in human brain microvascular endothelial cells using liquid chromatography-tandem mass spectrometry (LC-MS/MS)

Combination antiretroviral therapy (cART) regimens are recommended for HIV patients to better achieve and maintain plasma viral suppression. Despite adequate plasma viral suppression, HIV persists inside the brain, which is, in part thought to result from poor brain penetration of antiretroviral dru...

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Foilsithe in:Anal Chim Acta
Main Authors: Patel, Sulay H., Ismaiel, Omnia A., Mylott, William R, Yuan, Moucun, Hauser, Kurt F., McRae, MaryPeace
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486649/
https://ncbi.nlm.nih.gov/pubmed/30797464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2019.01.015
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