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Repeat expansion diseases

More than 40 diseases, most of which primarily affect the nervous system, are caused by expansions of simple sequence repeats dispersed throughout the human genome. Expanded trinucleotide repeat diseases were discovered first and remain the most frequent. More recently tetra-, penta-, hexa- and even...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Handb Clin Neurol
1. Verfasser: Paulson, Henry
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485936/
https://ncbi.nlm.nih.gov/pubmed/29325606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-444-63233-3.00009-9
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