Computational modeling of pancreatic cancer patients receiving FOLFIRINOX and gemcitabine-based therapies identifies optimum intervention strategies

Pancreatic ductal adenocarcinoma (PDAC) exhibits a variety of phenotypes with regard to disease progression and treatment response. This variability complicates clinical decision-making despite the improvement of survival due to the recent introduction of FOLFIRINOX (FFX) and nab-paclitaxel. Questio...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yamamoto, Kimiyo N., Nakamura, Akira, Liu, Lin L., Stein, Shayna, Tramontano, Angela C., Kartoun, Uri, Shimizu, Tetsunosuke, Inoue, Yoshihiro, Asakuma, Mitsuhiro, Haeno, Hiroshi, Kong, Chung Yin, Uchiyama, Kazuhisa, Gonen, Mithat, Hur, Chin, Michor, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485645/
https://ncbi.nlm.nih.gov/pubmed/31026288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215409
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