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Vaccination with a chikungunya virus-like particle vaccine exacerbates disease in aged mice

INTRODUCTION: Chikungunya virus (CHIKV) is a re-emerging pathogen responsible for causing outbreaks of febrile disease accompanied with debilitating joint pain. Symptoms typically persist for two weeks, but more severe and chronic chikungunya illnesses have been reported, especially in the elderly....

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Arévalo, Maria T., Huang, Ying, Jones, Cheryl A., Ross, Ted M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485612/
https://ncbi.nlm.nih.gov/pubmed/31026260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007316
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