Serine starvation induces stress and p53 dependent metabolic remodeling in cancer cells

Cancer cells acquire distinct metabolic adaptations to survive stress associated with tumour growth and to satisfy the anabolic demands of proliferation. The tumour suppressor protein p53 influences a range of cellular metabolic processes, including glycolysis(1,2) oxidative phosphorylation(3) (OXPH...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Maddocks, Oliver D. K., Berkers, Celia R., Mason, Susan M., Zheng, Liang, Blyth, Karen, Gottlieb, Eyal, Vousden, Karen H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485472/
https://ncbi.nlm.nih.gov/pubmed/23242140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11743
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