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Serine starvation induces stress and p53 dependent metabolic remodeling in cancer cells
Cancer cells acquire distinct metabolic adaptations to survive stress associated with tumour growth and to satisfy the anabolic demands of proliferation. The tumour suppressor protein p53 influences a range of cellular metabolic processes, including glycolysis(1,2) oxidative phosphorylation(3) (OXPH...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6485472/ https://ncbi.nlm.nih.gov/pubmed/23242140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11743 |
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