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Evaluation of deuterated (18)F- and (11)C-labeled choline analogs for cancer detection by positron emission tomography

PURPOSE: (11)C-Choline positron emission tomography (PET) has been exploited to detect the aberrant choline metabolism in tumors. Radiolabeled choline uptake within the imaging time is primarily a function of transport, phosphorylation and oxidation. Rapid choline oxidation, however, complicates int...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Witney, Timothy H., Alam, Israt S., Turton, David R., Smith, Graham, Carroll, Laurence, Brickute, Diana, Twyman, Frazer J., Nguyen, Quang-Dé, Tomasi, Giampaolo, Awais, Ramla O., Aboagye, Eric O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485417/
https://ncbi.nlm.nih.gov/pubmed/22235095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2462
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