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Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis

IL-10 is an anti-inflammatory cytokine produced in the joint in rheumatoid arthritis by macrophages and infiltrating blood lymphocytes. Regulation of its expression is poorly understood, but previous findings have suggested that physical interactions with T cells may play a role. This report investi...

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Detalhes bibliográficos
Main Authors: Foey, Andrew, Green, Patricia, Foxwell, Brian, Feldmann, Marc, Brennan, Fionula
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC64854/
https://ncbi.nlm.nih.gov/pubmed/11879539
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