Defining therapeutic targets by using adenovirus: Blocking NF-κB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators

Lignende værker

• Efficient adenoviral infection with IκBα reveals that macrophage tumor necrosis factor α production in rheumatoid arthritis is NF-κB dependent
  af: Foxwell, Brian, et al.
  Udgivet: (1998)
• Is NF-κB a useful therapeutic target in rheumatoid arthritis?
  af: Feldmann, M, et al.
  Udgivet: (2002)
• Adenoviral transgene delivery provides an approach to identifying important molecular processes in inflammation: evidence for heterogenecity in the requirement for NFκB in tumour necrosis factor production
  af: Foxwell, B., et al.
  Udgivet: (2000)
• The Toll-Like Receptor Adaptor Proteins MyD88 and Mal/TIRAP Contribute to the Inflammatory and Destructive Processes in a Human Model of Rheumatoid Arthritis
  af: Sacre, Sandra M., et al.
  Udgivet: (2007)
• T-cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NFκB: implications for rheumatoid arthritis
  af: Beech, Jonathan T, et al.
  Udgivet: (2006)