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Otx2 restricts entry to the mouse germline
The successful segregation of germ cells from somatic lineages is vital for sexual reproduction and species survival. In the mouse, primordial germ cells (PGCs), precursors of all germ cells, are induced from the post-implantation epiblast1. Induction requires BMP4 signalling to prospective PGCs2 an...
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| Publicado en: | Nature |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6485399/ https://ncbi.nlm.nih.gov/pubmed/30283136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0581-5 |
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