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Suppression of OVA-alum induced allergy by Heligmosomoides polygyrus products is MyD88-, TRIF-, Regulatory T- and B cell-independent, but is associated with reduced Innate Lymphoid Cell activation

The murine intestinal nematode Heligmosomoides polygyrus exerts multiple immunomodulatory effects in the host, including the suppression of allergic inflammation in mice sensitized to allergen presented with alum adjuvant. Similar suppression is attained by co-administration of H. polygyrus excretor...

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Détails bibliographiques
Publié dans:Exp Parasitol
Auteurs principaux: McSorley, Henry J., Blair, Natalie F., Robertson, Elaine, Maizels, Rick M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485390/
https://ncbi.nlm.nih.gov/pubmed/25728231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2015.02.009
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