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Suppression of OVA-alum induced allergy by Heligmosomoides polygyrus products is MyD88-, TRIF-, Regulatory T- and B cell-independent, but is associated with reduced Innate Lymphoid Cell activation

The murine intestinal nematode Heligmosomoides polygyrus exerts multiple immunomodulatory effects in the host, including the suppression of allergic inflammation in mice sensitized to allergen presented with alum adjuvant. Similar suppression is attained by co-administration of H. polygyrus excretor...

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Detalhes bibliográficos
Publicado no:Exp Parasitol
Main Authors: McSorley, Henry J., Blair, Natalie F., Robertson, Elaine, Maizels, Rick M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485390/
https://ncbi.nlm.nih.gov/pubmed/25728231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2015.02.009
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