Exercise promotes a cardioprotective gene program in resident cardiac fibroblasts

Exercise and heart disease both induce cardiac remodeling, but only disease causes fibrosis and compromises heart function. The cardioprotective benefits of exercise have been attributed to changes in cardiomyocyte physiology, but the impact of exercise on cardiac fibroblasts (CFs) is unknown. Here,...

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Опубликовано в: :JCI Insight
Главные авторы: Lighthouse, Janet K., Burke, Ryan M., Velasquez, Lissette S., Dirkx, Ronald A., Aiezza, Alessandro, Moravec, Christine S., Alexis, Jeffrey D., Rosenberg, Alex, Small, Eric M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485363/
https://ncbi.nlm.nih.gov/pubmed/30626739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92098
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