Exercise promotes a cardioprotective gene program in resident cardiac fibroblasts

Exercise and heart disease both induce cardiac remodeling, but only disease causes fibrosis and compromises heart function. The cardioprotective benefits of exercise have been attributed to changes in cardiomyocyte physiology, but the impact of exercise on cardiac fibroblasts (CFs) is unknown. Here,...

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Udgivet i:JCI Insight
Main Authors: Lighthouse, Janet K., Burke, Ryan M., Velasquez, Lissette S., Dirkx, Ronald A., Aiezza, Alessandro, Moravec, Christine S., Alexis, Jeffrey D., Rosenberg, Alex, Small, Eric M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485363/
https://ncbi.nlm.nih.gov/pubmed/30626739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92098
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