Acidic Microenvironment Up-Regulates Exosomal miR-21 and miR-10b in Early-Stage Hepatocellular Carcinoma to Promote Cancer Cell Proliferation and Metastasis

Rationale: The incidence of hepatocellular carcinoma is rising worldwide. It is predicted that nearly half of the early-stage hepatocellular carcinoma (E-HCC) patients will develop recurrence. Dysregulated pH, a hallmark of E-HCC, is correlated with poor prognosis. The acidic microenvironment has be...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Tian, Xiao-Peng, Wang, Chen-Yuan, Jin, Xiao-Han, Li, Mei, Wang, Feng-Wei, Huang, Wei-Juan, Yun, Jing-Ping, Xu, Rui-Hua, Cai, Qing-Qing, Xie, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485281/
https://ncbi.nlm.nih.gov/pubmed/31037150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30958
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