miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer

BACKGROUND: Phosphatase of regenerating liver-3 (PRL-3) is an oncogene known to promote tumour metastasis, especially in colorectal cancer (CRC). Here, we demonstrate that the miR-21, miR-17 and miR-19a expressions induced by PRL-3 are involved in the proliferation and metastasis of colon cancer. ME...

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Главные авторы: Zhang, J, Xiao, Z, Lai, D, Sun, J, He, C, Chu, Z, Ye, H, Chen, S, Wang, J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2012
Предметы:
Molecular Diagnostics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394980/
https://ncbi.nlm.nih.gov/pubmed/22677902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.251
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