Berberine Protects Glomerular Podocytes via Inhibiting Drp1-Mediated Mitochondrial Fission and Dysfunction

Elevated levels of plasma free fatty acid (FFA) and disturbed mitochondrial dynamics play crucial roles in the pathogenesis of diabetic kidney disease (DKD). However, the mechanisms by which FFA leads to mitochondrial damage in glomerular podocytes of DKD and the effects of Berberine (BBR) on podocy...

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Vydáno v:Theranostics
Hlavní autoři: Qin, Xin, Zhao, Yan, Gong, Jing, Huang, Wenya, Su, Hao, Yuan, Fen, Fang, Ke, Wang, Dingkun, Li, Jingbin, Zou, Xin, Xu, Lijun, Dong, Hui, Lu, Fuer
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485199/
https://ncbi.nlm.nih.gov/pubmed/31037132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30640
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