Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance

Rationale: Dysregulated microRNA (miRNA) expressions in cancer can contribute to chemoresistance. This study aims to identify miRNAs that are associated with fluorouracil (5-FU) chemoresistance in esophageal squamous cell carcinoma (ESCC). The potential of miR-29c as a novel diagnostic, prognostic a...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Li, Bin, Hong, Pan, Zheng, Can-Can, Dai, Wei, Chen, Wen-You, Yang, Qing-Sheng, Han, Liang, Tsao, Sai Wah, Chan, Kin Tak, Lee, Nikki Pui Yue, Law, Simon, Xu, Li Yan, Li, En Min, Chan, Kwok Wah, Qin, Yan Ru, Guan, Xin Yuan, Lung, Maria Li, He, Qing-Yu, Xu, Wen Wen, Cheung, Annie LM
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2019
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485198/
https://ncbi.nlm.nih.gov/pubmed/31037126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30372
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