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Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson’s disease with cognitive decline

Although the precise neuropathological substrates of cognitive decline in Parkinson’s disease (PD) remain elusive, it has long been regarded that pathology in the CA2 hippocampal subfield is characteristic of Lewy body dementias, including dementia in PD (PDD). Early non-human primate tracer studies...

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Publicado en:Acta Neuropathol Commun
Autores principales: Liu, Alan King Lun, Chau, Tsz Wing, Lim, Ernest Junwei, Ahmed, Idil, Chang, Raymond Chuen-Chung, Kalaitzakis, Michail E., Graeber, Manuel B., Gentleman, Steve M., Pearce, Ronald K. B.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485180/
https://ncbi.nlm.nih.gov/pubmed/31023342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0717-3
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