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A Markov chain Monte Carlo method for estimating the statistical significance of proteoform identifications by top-down mass spectrometry

Top-down mass spectrometry is capable of identifying whole proteoform sequences with multiple post-translational modifications because it generates tandem mass spectra directly from intact proteoforms. Many software tools, such as ProSightPC, MSPathFinder, and TopMG, have been proposed for identifyi...

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Bibliografiske detaljer
Udgivet i:J Proteome Res
Main Authors: Kou, Qiang, Wang, Zhe, Lubeckyj, Rachele A., Wu, Si, Sun, Liangliang, Liu, Xiaowen
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484843/
https://ncbi.nlm.nih.gov/pubmed/30638379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00562
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