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Deep top-down proteomics using capillary zone electrophoresis-tandem mass spectrometry: identification of 5700 proteoforms from the Escherichia coli proteome

Capillary zone electrophoresis (CZE)-tandem mass spectrometry (MS/MS) has been recognized as a useful tool for top-down proteomics. However, its performance for deep top-down proteomics is still dramatically lower than widely used reversed-phase liquid chromatography (RPLC)-MS/MS. We present an orth...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: McCool, Elijah N., Lubeckyj, Rachele A., Shen, Xiaojing, Chen, Daoyang, Kou, Qiang, Liu, Xiaowen, Sun, Liangliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930140/
https://ncbi.nlm.nih.gov/pubmed/29620868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b00693
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